Best Peptides for Sexual Health

Research compounds for sexual function and libido - PT-141, kisspeptin, melanotan II with dosing protocols.

PT-141 (Bremelanotide)

A synthetic melanocortin peptide FDA-approved for HSDD in premenopausal women. Works through CNS to enhance sexual desire rather than vascular mechanisms.

Dose: 1.75 mg | Route: Subcutaneous injection

Read full PT-141 (Bremelanotide) guide →

Melanotan II

A synthetic cyclic alpha-MSH analog with potent melanocortin activity. Known for tanning and sexual function effects through MC1R/MC3R/MC4R activation. Parent compound of PT-141.

Dose: 0.25-1 mg | Route: Subcutaneous injection

Read full Melanotan II guide →

Gonadorelin

A synthetic analog of gonadotropin-releasing hormone used diagnostically and therapeutically. Stimulates pulsatile LH and FSH release to maintain natural hormone production.

Dose: 100-500 mcg | Route: Subcutaneous injection

Read full Gonadorelin guide →

Kisspeptin-10

The shortest bioactive kisspeptin fragment, a master regulator of reproduction. Activates GnRH neurons to stimulate the HPG axis, increasing LH, FSH, and sex hormones.

Dose: 1-10 nmol/kg | Route: IV or Subcutaneous

Read full Kisspeptin-10 guide →

Oxytocin

A nonapeptide hormone with roles in bonding, reproduction, and uterine contraction. Intranasal form researched for enhancing intimacy, trust, and social cognition.

Dose: 20-40 IU intranasal | Route: Intranasal or IV (obstetric)

Read full Oxytocin guide →

Tadalafil Peptide

An experimental peptide-drug conjugate combining tadalafil with cell-penetrating peptides for targeted delivery and reduced systemic side effects.

Dose: 1-5 mg equivalent | Route: Topical or local injection

Read full Tadalafil Peptide guide →

TriMix

A compounded injectable combining three vasodilators for erectile dysfunction. One of the most effective ED treatments available through telemedicine clinics, used when oral PDE5 inhibitors are insuff

Dose: 0.1-0.5 mL (titrated) | Route: Intracavernosal injection

Read full TriMix guide →

Tadalafil

A long-acting PDE5 inhibitor prescribed by telemedicine clinics for erectile dysfunction and daily low-dose cardiovascular/prostate health. Its 36-hour duration of effect earned it the nickname "

Dose: 2.5-5 mg daily or 10-20 mg as needed | Route: Oral tablet

Read full Tadalafil guide →

Alprostadil

A synthetic form of prostaglandin E1 used to treat erectile dysfunction by directly relaxing penile blood vessels. It works independently of sexual arousal and is delivered by injection or urethral su

Dose: Provider-titrated per response | Route: Intracavernosal injection or urethral pellet

Read full Alprostadil guide →

Prostamax

A short peptide bioregulator from the Khavinson family targeted at prostate tissue. Used in the bioregulator community to support prostate function and male urogenital health in short repeated courses

Dose: ~1-2 capsules/day or short injectable courses | Route: Oral capsule or subcutaneous

Read full Prostamax guide →

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