Best Peptides for Muscle Growth

Performance peptides for lean muscle gain in research - follistatin, IGF-1 LR3, MK-677, and growth hormone secretagogues.

Follistatin 344

A naturally occurring glycoprotein that binds and neutralizes myostatin and activin. The longest isoform enabling significant muscle hypertrophy by removing growth inhibitors.

Dose: 100-200 mcg | Route: Subcutaneous

Read full Follistatin 344 guide →

IGF-1 LR3

A modified IGF-1 with R3 substitution and N-terminal extension reducing IGFBP binding, increasing half-life and potency 2-3x over native IGF-1.

Dose: 20-50 mcg | Route: Subcutaneous or intramuscular injection

Read full IGF-1 LR3 guide →

MK-677 (Ibutamoren)

An orally active non-peptide GH secretagogue that mimics ghrelin signaling. Increases GH and IGF-1 for 24 hours from a single oral dose.

Dose: 10-25 mg | Route: Oral (capsule/liquid)

Read full MK-677 (Ibutamoren) guide →

Ipamorelin

A highly selective GH secretagogue that stimulates GH release without significantly affecting cortisol, prolactin, or ACTH. Considered the cleanest GHRP.

Dose: 100-300 mcg | Route: Subcutaneous injection

Read full Ipamorelin guide →

CJC-1295

A synthetic GHRH analog with 4 amino acid substitutions for stability. Often combined with DAC for extended half-life or used without DAC for pulsatile release.

Dose: 100-300 mcg | Route: Subcutaneous injection

Read full CJC-1295 guide →

Sermorelin

The biologically active fragment of GHRH (first 29 amino acids). Previously FDA-approved for GH deficiency in children. Stimulates natural pulsatile GH release. Now available through compounding pharm

Dose: 200-300 mcg | Route: Subcutaneous injection

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Tesamorelin

A synthetic GHRH analog FDA-approved for HIV-associated lipodystrophy. Particularly effective at reducing visceral adipose tissue with emerging cognitive benefits.

Dose: 2 mg | Route: Subcutaneous injection

Read full Tesamorelin guide →

GHRP-2

A synthetic hexapeptide and one of the most potent GHRPs. Produces strong GH release but also modestly increases cortisol and prolactin.

Dose: 100-300 mcg | Route: Subcutaneous

Read full GHRP-2 guide →

GHRP-6

One of the original synthetic GH releasing peptides. Strongly stimulates appetite through ghrelin pathways while promoting robust GH release.

Dose: 100-300 mcg | Route: Subcutaneous

Read full GHRP-6 guide →

Hexarelin

The most potent synthetic GHRP with unique cardioprotective properties independent of GH release through cardiac CD36 receptor binding.

Dose: 100-200 mcg | Route: Subcutaneous

Read full Hexarelin guide →

CJC-1295 DAC

CJC-1295 conjugated with DAC that binds albumin, extending half-life to ~8 days. Creates sustained GH elevation rather than pulsatile release.

Dose: 2 mg | Route: Subcutaneous

Read full CJC-1295 DAC guide →

ACE-031

A soluble ActRIIB-Fc fusion acting as ligand trap for myostatin, activin, and GDF-11. Removes multiple negative regulators of muscle growth simultaneously.

Dose: 0.3-3 mg/kg | Route: Subcutaneous

Read full ACE-031 guide →

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