Follistatin 344 Research Guide

Full name: Follistatin 344 (FST-344)

A naturally occurring glycoprotein that binds and neutralizes myostatin and activin. The longest isoform enabling significant muscle hypertrophy by removing growth inhibitors.

How Follistatin 344 Works

Binds myostatin and activin A with high affinity, preventing ActRIIB receptor activation. Removes the brake on muscle growth allowing uninhibited satellite cell proliferation.

Dosing Protocol

• Typical dose: 100-200 mcg
• Frequency: Daily for 10-30 days
• Duration: 10-30 day protocols
• Route: Subcutaneous

Reported Benefits

• Significant muscle growth
• Myostatin inhibition
• Increased strength
• Activin neutralization
• Enhanced recovery

Potential Side Effects

• Limited safety data
• Theoretical reproductive effects
• Joint stress from rapid gains
• Cardiac muscle effects (theoretical)

Research Citations

1. Follistatin gene therapy for muscle wasting (2022) - AAV-delivered FST-344 increased quadriceps volume by 15% in Becker MD patients.
2. Myostatin inhibition by follistatin in primates (2020) - Increased lean muscle by 20% without significant off-target effects over 8 weeks.

Related Muscle Growth Compounds

• ACE-031 - Full Profile
• IGF-1 LR3 - Full Profile
• MGF (Mechano Growth Factor) - Full Profile
• Myostatin Inhibitor - Full Profile
• LGD-4033 - Full Profile
• YK-11 - Full Profile

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