Follistatin 344 vs YK-11
A side-by-side research comparison of Follistatin 344 and YK-11 across mechanism, dosing, half-life, benefits, side effects and research status.
Comparison table
| Attribute | Follistatin 344 | YK-11 |
|---|---|---|
| Full name | Follistatin 344 (FST-344) | YK-11 (Myostatin Inhibitor / SARM) |
| Category | Muscle Growth | Muscle Growth |
| Status | Research compound | Research compound |
| Mechanism | Binds myostatin and activin A with high affinity, preventing ActRIIB receptor activation. Removes the brake on muscle growth allowing uninhibited satellite cell proliferation. | Partial androgen receptor agonist that induces follistatin expression, creating dual myostatin inhibition and AR activation. |
| Molecular weight | 36,000 Da | 430.54 Da |
| Half-life | 2-4 hours | ~6-10 hours |
| Bioavailability | Moderate (SubQ) | ~70% oral |
| Typical dose | 100-200 mcg | 5-10 mg |
| Frequency | Daily for 10-30 days | Once daily |
| Route | Subcutaneous | Oral |
Follistatin 344 reported benefits
- Significant muscle growth
- Myostatin inhibition
- Increased strength
- Activin neutralization
- Enhanced recovery
YK-11 reported benefits
- Dual anabolic mechanism
- Follistatin induction
- Oral convenience
- Muscle hardening
Related comparisons
Research and educational reference only. Not medical advice.