Taurine Research Guide

Full name: Taurine (2-Aminoethanesulfonic Acid)

A conditionally essential amino acid concentrated in muscle, brain, heart, and blood cells. Circulating taurine declines with age, and a landmark 2023 study showed taurine supplementation extended healthspan and lifespan in multiple species, making it a core longevity supplement for biohackers.

How Taurine Works

Acts as a cytoprotective osmolyte and antioxidant, stabilizes mitochondrial function, modulates calcium signaling and GABA-A/glycine receptors, reduces inflammation, and supports bile acid conjugation. Taurine deficiency accelerates cellular senescence markers.

Dosing Protocol

• Typical dose: 1-6 g per day
• Frequency: 1-3x daily
• Duration: Ongoing
• Route: Oral (powder or capsule)

Reported Benefits

• Supports mitochondrial function
• Cardiovascular and blood pressure support
• Exercise endurance
• Antioxidant and anti-inflammatory
• Longevity/healthspan signal
• Calming/GABAergic effects

Potential Side Effects

• Generally very well tolerated
• Mild GI upset at high doses
• Rare loose stools

Research Citations

1. Taurine deficiency as a driver of aging (2023) - Taurine supplementation increased healthy lifespan by ~10-12% in mice and improved multiple aging biomarkers across species.
2. Taurine and cardiovascular health (2021) - Supplementation lowered blood pressure and improved endothelial function in hypertensive subjects.

Related Anti-Aging Compounds

• Epithalon - Full Profile
• NAD+ - Full Profile
• Humanin - Full Profile
• FOXO4-DRI - Full Profile
• SS-31 (Elamipretide) - Full Profile
• GDF-11 - Full Profile

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