Selank Research Guide

Full name: Selank (TP-7)

A synthetic analog of tuftsin with Pro-Gly-Pro for stability. Developed at the Russian Academy of Sciences with anxiolytic and nootropic properties without sedation or addiction.

How Selank Works

Modulates GABA-A allosteric sites, increases BDNF, stabilizes enkephalin degradation, and influences serotonin metabolism. Enhances IL-6 and Th1/Th2 balance.

Dosing Protocol

• Typical dose: 250-750 mcg per spray dose
• Frequency: 2-3x daily
• Duration: 2-4 week courses
• Route: Intranasal spray

Reported Benefits

• Anxiolytic without sedation
• Improved memory/learning
• Cognitive flexibility
• Immune modulation
• BDNF upregulation
• No addiction

Potential Side Effects

• Nasal irritation
• Mild fatigue (initial)
• Headache (rare)

Research Citations

1. Selank anxiolytic effects vs benzodiazepines (2021) - Equivalent anxiolysis to diazepam in GAD without cognitive impairment or dependence over 8 weeks.
2. BDNF modulation by selank (2020) - Increased hippocampal BDNF by 60% and improved spatial memory by 35% in aged models.

Related Cognitive & Nootropic Compounds

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