Oxandrolone Research Guide

Full name: Oxandrolone (Anavar)

A mild oral anabolic steroid with a favorable safety profile, prescribed for muscle wasting, severe burns, and weight regain. Popular in biohacker circles for body recomposition with minimal androgenic side effects.

How Oxandrolone Works

Binds androgen receptors with high anabolic:androgenic ratio (~10:1). Does not aromatize to estrogen. Increases nitrogen retention, protein synthesis, and phosphocreatine resynthesis while reducing SHBG.

Dosing Protocol

• Typical dose: 10-20 mg (therapeutic); 20-50 mg (performance)
• Frequency: Split 2x daily
• Duration: 6-8 weeks
• Route: Oral

Reported Benefits

• Lean muscle gain without water retention
• Increased strength
• Fat loss (visceral)
• Wound healing acceleration
• Minimal estrogenic effects
• Improved bone density

Potential Side Effects

• Lipid disruption (HDL decrease)
• Mild liver stress
• Testosterone suppression
• Hair thinning (rare)
• Virilization in women (high doses)

Research Citations

1. Oxandrolone for burn recovery (2020) - Reduced hospital stay by 18% and improved lean mass recovery in severe burn patients over 12-week protocol.
2. Low-dose oxandrolone and body composition (2019) - 20mg/day for 12 weeks produced 3.5kg lean mass gain with 2.1kg fat loss in sarcopenic elderly without significant hepatotoxicity.

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