Harmaline Research Guide

Full name: Harmaline (harmala alkaloid)

A natural compound from Syrian rue and the ayahuasca vine. It is an MAO inhibitor that makes oral DMT active, and at higher doses produces its own dreamy, sedating effects.

How Harmaline Works

Inhibits the enzyme MAO-A, which lets oral DMT work; also has mild psychedelic and sedative effects of its own.

Dosing Protocol

• Typical dose: Varies by individual and setting
• Frequency: Occasional
• Duration: Acute effects last 4-8 hours
• Route: Oral

Reported Benefits

• Enables oral DMT (ayahuasca)
• Studied in ethnobotany
• Natural harmala alkaloid
• Dreamy effects at higher doses

Potential Side Effects

• Dangerous MAOI food and drug interactions
• Strong nausea and vomiting
• Sedation
• Tremor

Related Psychedelics Compounds

• MDMA - Full Profile
• Psilocybin - Full Profile
• LSD - Full Profile
• Ibogaine - Full Profile
• DMT - Full Profile
• Ayahuasca - Full Profile

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