DOB (2,5-Dimethoxy-4-bromoamphetamine)

Category: Psychedelics. Status: Schedule I (research compound).

A potent, long-lasting DOx psychedelic active at very small doses. Known for strong vasoconstriction, which has caused injuries at high doses.

How it works

Activates serotonin 5-HT2A receptors; potent and very long-acting.

Key facts

• Molecular weight: 274.15 g/mol
• Half-life: Long
• Bioavailability: Oral
• Storage: Research/reference only.

Dosing overview

• Typical dose: Varies by individual and setting
• Frequency: Occasional
• Duration: Acute effects last 12-24 hours
• Route: Oral

Protocol notes

• Taken orally and active at tiny doses, so accurate measuring is critical.
• Strong blood-vessel narrowing means high doses can damage limbs; doses are kept low.

Reported benefits

• Active at microgram-to-low-mg doses
• Very long experience
• DOx research compound
• Strong visuals

Possible side effects

• Severe vasoconstriction at high doses
• Very long duration
• Anxiety
• Raised blood pressure

Compare DOB

• DOB vs MDMA
• DOB vs Psilocybin
• DOB vs LSD
• DOB vs Ibogaine
• DOB vs DMT
• DOB vs Ayahuasca

Research and educational reference only. Not medical advice.