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GHRP-2 vs Ipamorelin

A side-by-side research comparison of GHRP-2 and Ipamorelin across mechanism, dosing, half-life, benefits, side effects and research status.

Comparison table

AttributeGHRP-2Ipamorelin
Full nameGrowth Hormone Releasing Peptide-2 (Pralmorelin)Ipamorelin (Selective GH Secretagogue)
CategoryGrowth HormoneGrowth Hormone
StatusResearch compoundResearch compound
MechanismPotent GHSR-1a agonist stimulating GH release and appetite. Also mildly stimulates ACTH/cortisol release.Selectively activates GHSR on pituitary somatotrophs. Unlike GHRP-6 and hexarelin, does not significantly activate ACTH or prolactin-releasing pathways.
Molecular weight818 Da711.9 Da
Half-life1-2 hours2 hours
BioavailabilityHigh (SubQ)High (SubQ)
Typical dose100-300 mcg100-300 mcg
Frequency2-3x daily1-3x daily
RouteSubcutaneousSubcutaneous injection

GHRP-2 reported benefits

  • Strongest GH release among GHRPs
  • Appetite stimulation
  • Recovery improvement
  • Enhanced sleep
  • Muscle preservation

Ipamorelin reported benefits

  • Clean GH release
  • No cortisol or prolactin increase
  • Improved sleep
  • Fat loss
  • Joint support
  • Anti-aging benefits

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Research and educational reference only. Not medical advice.