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5-MeO-DMT vs DPT

A side-by-side research comparison of 5-MeO-DMT and DPT across mechanism, dosing, half-life, benefits, side effects and research status.

Comparison table

Attribute5-MeO-DMTDPT
Full name5-Methoxy-N,N-dimethyltryptamineN,N-Dipropyltryptamine
CategoryPsychedelicsPsychedelics
StatusSchedule I (research compound)Schedule I (research compound)
MechanismStrongly activates serotonin 5-HT1A and 5-HT2A receptors, producing rapid and intense changes in consciousness.Activates serotonin 5-HT2A receptors.
Molecular weight218.30 g/mol244.38 g/mol
Half-lifeShort (minutes)Short
BioavailabilityInhaled/injectedOral
Typical doseLow milligram range in clinical studiesVaries by individual and setting
FrequencyOne to a few supervised sessionsOccasional
RouteInhalation or injection in research settingsOral

5-MeO-DMT reported benefits

  • Studied for treatment-resistant depression
  • Short duration suits clinical use
  • Explored for anxiety
  • Rapid onset of effects

DPT reported benefits

  • Explored in end-of-life therapy
  • Used in some religious contexts
  • Shorter than ayahuasca
  • Tryptamine research compound

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Research and educational reference only. Not medical advice.