ResearchSafe

DPT (N,N-Dipropyltryptamine)

Category: Psychedelics. Status: Schedule I (research compound).

A short-to-moderate acting tryptamine that has been explored in religious and end-of-life therapy settings. Effects are often described as intense and auditory.

How it works

Activates serotonin 5-HT2A receptors.

Key facts

  • Molecular weight: 244.38 g/mol
  • Half-life: Short
  • Bioavailability: Oral
  • Storage: Research/reference only.

Dosing overview

  • Typical dose: Varies by individual and setting
  • Frequency: Occasional
  • Duration: Acute effects last 2-4 hours
  • Route: Oral

Protocol notes

  • Insufflated, smoked or taken orally; has been used in guided religious and end-of-life settings.
  • Shorter than ayahuasca, but effects can be intense and disorienting.

Reported benefits

  • Explored in end-of-life therapy
  • Used in some religious contexts
  • Shorter than ayahuasca
  • Tryptamine research compound

Possible side effects

  • Intense, sometimes frightening experiences
  • Nausea
  • Raised heart rate
  • Limited human safety data

Community reviews of DPT

Rated 4.5 out of 5 from 2 community reviews by ResearchSafe members.

  • labrat_runner rated it 4/5 - More mental clarity during night shifts: For me, DPT mostly opened up a quiet mental space that let me sort through stressful shift memories without the usual fog, so when I finally got home I could actually relax and sleep. The trips were short, a bit intense at first, but manageable. đź’‰
  • kim609 rated it 5/5 - clearer mind and less rumination after a single DPT session: after a 3‑week trial i found my usual night‑time overthinking softened dramatically; thoughts settled quicker and i felt a gentle spaciousness that let me drift to sleep without the usual mental chatter. for what it is worth, it was a surprisingly soothing shift.

Compare DPT

Research and educational reference only. Not medical advice.