RAD-140 (Testolone) (Testolone (RAD-140))
A potent selective androgen receptor modulator (SARM) studied for strong anabolic effects on muscle. It is not approved for human use, is banned in sport, and carries notable suppression and liver-stress concerns.
How it works
Acts as a strong, tissue-selective androgen receptor agonist in muscle and bone, driving anabolic signaling with a higher anabolic-to-androgenic ratio than testosterone in preclinical models.
Key facts
- Molecular weight: 393.83 Da
- Half-life: ~16-20 hours
- Bioavailability: Oral
- Storage: Keep cool, dry, and sealed; protect from light.
Dosing overview
- Typical dose: Commonly cited 5-15 mg/day (research)
- Frequency: Once daily
- Duration: Commonly cited 6-10 week cycles
- Route: Oral
Protocol notes
- Once-daily oral dosing is typical.
- Reported as more suppressive than Ostarine; users plan a recovery/PCT phase.
- Regular bloodwork (testosterone, lipids, liver markers) is strongly advised.
Reported benefits
- Strong lean muscle gains (research)
- Increased strength
- Studied originally for muscle wasting and breast cancer
- Bone-supportive signaling
Possible side effects
- Marked testosterone suppression
- Liver enzyme elevation
- Lowered HDL cholesterol
- Aggression/mood changes
- Potential hair shedding
Research
- RAD-140 preclinical anabolic profile (2011): Showed potent, tissue-selective anabolic activity in muscle with reduced prostate effects in primates.
Compare RAD-140 (Testolone)
Research and educational reference only. Not medical advice.