ResearchSafe

MDA (3,4-Methylenedioxyamphetamine (sass))

Category: Psychedelics. Status: Schedule I (research compound).

A close relative of MDMA that leans more psychedelic, with more visuals and a longer, more stimulating effect. Studied historically and known for greater neurotoxicity risk than MDMA.

How it works

Releases serotonin, dopamine and norepinephrine and has direct serotonin receptor activity, giving a mix of empathogenic and psychedelic effects.

Key facts

  • Molecular weight: 179.22 g/mol
  • Half-life: ~6-8 hours
  • Bioavailability: Oral
  • Storage: Research/reference only.

Dosing overview

  • Typical dose: Varies by individual and setting
  • Frequency: Occasional
  • Duration: Acute effects last 6-8 hours
  • Route: Oral

Protocol notes

  • Taken orally as powder or capsule; more visual and longer than MDMA.
  • Carries a higher overheating and neurotoxicity risk, so people hydrate sensibly and avoid redosing.

Reported benefits

  • More visual than MDMA
  • Empathogen-psychedelic blend
  • Longer-lasting
  • Historic research compound

Possible side effects

  • Greater neurotoxicity risk than MDMA
  • Overheating
  • Raised heart rate and blood pressure
  • Low mood afterward

Compare MDA

Research and educational reference only. Not medical advice.