LSZ (Lysergic acid 2,4-dimethylazetidide)
A rigid LSD analog created to study the shape of the LSD molecule at its receptor. Effects are very LSD-like with a slightly shorter duration.
How it works
Activates serotonin 5-HT2A receptors; designed to lock the molecule into one shape.
Key facts
- Molecular weight: 349.47 g/mol
- Half-life: ~3-4 hours
- Bioavailability: Oral
- Storage: Research/reference only.
Dosing overview
- Typical dose: Varies by individual and setting
- Frequency: Occasional
- Duration: Acute effects last 6-10 hours
- Route: Oral
Protocol notes
- Taken orally on blotter or as liquid, very similar to LSD with a slightly shorter run.
Reported benefits
- Very LSD-like
- Used in receptor research
- Strong visuals
- Lysergamide research compound
Possible side effects
- Anxiety
- Raised heart rate
- Body load
- Limited human data
Community reviews of LSZ
- honest_cycles rated it 4/5 - Clearer Focus in My Creative Work After LSZ: For me, the biggest shift was a surprisingly steady, vivid focus during my writing sessions; ideas linked smoother and I felt less distracted. The visuals were present but gentle, and after three weeks I noticed the effect faded a little, so I rate it four stars.
- cole_recovery rated it 5/5 - visual clarity boost helped my coding flow: anecdotally, after three weeks with lsz I noticed my visual thinking became unusually sharp, almost like watching code in my mind’s eye, which made debugging long sessions feel easier. it was subtle but consistent, and i felt more creative during both work and training.
- grinder_daily rated it 4/5 - LSD‑like clarity for my research grind: After a month on LSZ, I noticed my focus sharpened during late‑night data crunches, and the usual mental fog from pulling double shifts lifted a bit. The visuals were intense but manageable, and I slept okay. Just wish the comedown wasn’t a little sticky.
Compare LSZ
Research and educational reference only. Not medical advice.