ALD-52 (1-Acetyl-LSD)
An LSD relative (also called 1A-LSD) thought to convert into LSD in the body. Reported to be slightly gentler and more "clear" than LSD by some users.
How it works
Likely a prodrug for LSD acting on serotonin 5-HT2A receptors.
Key facts
- Molecular weight: 349.43 g/mol
- Half-life: ~3-5 hours
- Bioavailability: Oral
- Storage: Research/reference only.
Dosing overview
- Typical dose: Varies by individual and setting
- Frequency: Occasional
- Duration: Acute effects last 8-12 hours
- Route: Oral
Protocol notes
- Taken orally on blotter, used just like LSD with a similar long duration.
Reported benefits
- LSD-like experience
- Reported slightly gentler
- Lysergamide research compound
- Long duration
Possible side effects
- Long, intense experiences
- Anxiety
- Raised heart rate and blood pressure
- Limited human data
Community reviews of ALD-52
- aisha_hikes rated it 3/5 - Slightly smoother mental clarity after a month, but not life‑changing: Over four weeks I noticed a modest lift in mental focus on days I felt a bit foggy, especially before night shifts, but the effect faded quickly and didn’t translate into any lasting mood boost or creative spark for me.
- chemist_daily rated it 4/5 - My ALD-52 experience with grad school stress: The biggest thing for me was how much gentler the headspace felt? Fwiw, it seemed to make my research reading way more fluid and less overwhelming. It could just be placebo, but I felt less anxious than usual? I just wish the duration was a bit shorter 😅.
- rachel266 rated it 2/5 - Felt no real mental clarity, just lingering fatigue: I tried ALD‑52 hoping it would help me focus after long shifts, but the trip was muted and left me unusually tired the next day. For me the only noticeable change was a vague heaviness, not the sharp insight I had expected.
Compare ALD-52
Research and educational reference only. Not medical advice.