ResearchSafe

2C-B (4-Bromo-2,5-dimethoxyphenethylamine)

Category: Psychedelics. Status: Schedule I (research compound).

A popular phenethylamine psychedelic first made by chemist Alexander Shulgin. Known for colorful visuals and an upbeat, sensual, manageable experience at common doses.

How it works

Activates serotonin 5-HT2A receptors. A phenethylamine rather than a tryptamine.

Key facts

  • Molecular weight: 260.16 g/mol
  • Half-life: ~2 hours
  • Bioavailability: Oral
  • Storage: Research/reference only.

Dosing overview

  • Typical dose: Varies by individual and setting
  • Frequency: Occasional
  • Duration: Acute effects last 4-6 hours
  • Route: Oral

Protocol notes

  • Taken orally as a measured dose (powder, capsule or pill) for a colorful, upbeat 4-6 hour experience.
  • Sometimes used socially because it is shorter and gentler than LSD.
  • Dose is very sensitive, so people measure carefully.

Reported benefits

  • Colorful, gentle visuals
  • Upbeat and sociable
  • Shorter than LSD
  • Well-studied Shulgin compound

Possible side effects

  • Anxiety at higher doses
  • Nausea
  • Raised heart rate and blood pressure
  • Dose-sensitive

Community reviews of 2C-B

Rated 3 out of 5 from 2 community reviews by ResearchSafe members.

  • kayla270 rated it 4/5 - Brightened Afternoon Slump After Training: After a heavy leg day, a low 2C‑B dose turned my post‑workout fatigue into a light, buzzing focus that let me finish paperwork without the usual brain fog, and the colours in the lab seemed a bit sharper, still a bit twitchy, but overall pleasant.
  • quiet_longevity568 rated it 2/5 - Felt More Foggy Than Colorful, Disappointed: I tried 2C‑B hoping for a light mood lift before a sales conference, but the only noticeable thing was a mild head pressure and a brief, blurry color shift that faded fast. It didn’t help my confidence or social ease, and I felt a little off afterwards.

Compare 2C-B

Research and educational reference only. Not medical advice.