Palmitoyl Tetrapeptide-7 Research Guide

Full name: Palmitoyl Tetrapeptide-7 (Pal-GQPR)

A lipopeptide that reduces IL-6 secretion and inflammaging. Often paired with Pal-Tripeptide-1 as "Matrixyl 3000" for combined collagen-building and anti-inflammatory action.

How Palmitoyl Tetrapeptide-7 Works

Inhibits IL-6 release from keratinocytes and reduces inflammation-mediated MMP activation, preserving existing collagen while complementing Pal-GHK collagen building.

Dosing Protocol

• Typical dose: 2-4% in formulation
• Frequency: 1-2x daily
• Duration: 8-16 weeks
• Route: Topical

Reported Benefits

• Anti-inflammatory (skin)
• Reduces IL-6
• Prevents collagen degradation
• Combats inflammaging

Potential Side Effects

• Extremely well tolerated
• No significant reports

Research Citations

1. Anti-inflammatory effects of Pal-GQPR on UV-damaged skin (2021) - Reduced UV-induced IL-6 by 55% and MMP-1 by 35% in irradiated keratinocytes.
2. Inflammaging modulation by cosmeceutical peptides (2022) - Significantly reduced inflammatory markers in chronological and photoaging clinical evaluation.

Related Skin & Anti-Aging Compounds

• Copper Peptides - Full Profile
• Matrixyl - Full Profile
• Argireline - Full Profile
• Leuphasyl - Full Profile
• SNAP-8 - Full Profile
• Palmitoyl Tripeptide-1 - Full Profile

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