Camaro 15 mg Tirzepatide, plateau and nausea after 4 months

Posted by liam_sleepnerd in Weight Loss & Metabolic - 1 points, 0 comments.

I began compounded tirzepatide at 2.5 mg weekly six months ago, logging weight, HRV, and GI symptoms daily. After 8 weeks I titrated to 5 mg, saw a steady drop of 3 kg, and HRV increased from 48 ms to 65 ms. At week 12 I pushed to 10 mg, weight fell another 2 kg, but nausea became constant, especially after meals. The GI side‑effects peaked around week 14, but my HRV dipped back to 55 ms, and the weight loss plateaued at a 12 % total from baseline.

I elected to hold at 10 mg for two more weeks, which helped the nausea ease, but the weight stayed flat. Then I reduced to 7.5 mg and noticed appetite returning slightly, and weight began to creep down again, now 0.5 kg in the last week. My question: have others hit a similar plateau at 10 mg and found that a small de‑titration helps break it? Also, did anyone use any supportive GI meds without compromising the metabolic benefits? I stay off OTC anti‑emetics and keep a low‑carb dinner to see if that mitigates nausea while still staying in the weight‑loss window.

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