ResearchSafe

First Month on CagriSema – Appetite, Nausea, and HRV Trend

Posted by liam_sleepnerd in Weight Loss & Metabolic - 1 points, 0 comments.

4 mg once weekly, hoping the amylin mimic would hit the satiety center harder. Within the first three weeks I cut my usual dinner calories from 700 to 500, and the first week I felt a consistent fullness after just the first bite, tbh it was a game changer. The nausea started around the second dose, mild and resolved after a couple of meals; I did a half‑dose the first week to ease into it.

I’ve been logging HRV on my smartwatch and noticed a 5‑bpm increase in mean HRV over the first month, which aligns with my feeling of less stress. After four weeks I’m down 9 lbs and still on the same dose. I’d love to hear if anyone else has seen similar appetite suppression or HRV changes, and what they did for the nausea.

Community discussion - research and educational context only. Not medical advice.