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Cardarine 10mg daily: appetite spike and weight‑loss plateau?

Posted by dailyrenee in Weight Loss & Metabolic - 2 points, 4 comments.

I’ve been running 10km a day, feeling decent, but the scale stopped budging after I added Cardarine 10 mg. The literature says it should boost fat oxidation, yet my hunger doubled. I’m not a miracle worker, just an EMT‑P with a skinny belly that won’t quit.

I started on 10 mg, went to 15 mg after three weeks, monitoring liver enzymes, HRV, and sleep. All normal. Side effects? Mild nausea and a skin rash that cleared in two days. No serious trouble, but the appetite spike is real. At this point, I’m on a low‑carb diet, still not seeing a drop. Am I over‑dosing? Or is this just a placeboish oddity?

I saw some posts about pairing Cardarine withluv amlexanox or 5‑Amino‑1MQ. Anyone tried that to reset metabolism or curb appetite? I’ve got the weight log and HRV trend to share if it helps. No promises, just data. Howzit?

Comments

  • aspiring_trailrun: I’ve been on Cardarine for almost a month on my own track and the appetite spike was real for me Beard‑to‑beard too. My weight didn’t budge and I felt a mild energy drop that made me reach for carbs. I ended up cutting the dose back to 5 mg and re‑introducing a small, high‑protein snack after runs; the hunger eased and the scale finally Bara. I haven’t mixed it with amlexanox or 5‑AMG yet – the data looks shaky and I’m wary of extra drugs. Have you tweaked meal timing or added a protein‑shake p
  • hank_m: Tbh i’ve been on cardarine 10 mg for a bit and i’ve had the same hunger spike, even with a low‑carb plan, so it ain’t just a placebo thing, it’s real for me too; i think what’s happening is the drug ups your fat oxidation and you’re burning through what would normally be stored carbs, so the body is sending a signal that it needs more energy – basically a metabolic reset. I haven’t gone over the 10–15 mg range, but i did cut back on overall calories for a week and saw a tiny dip on the scale, so
  • dailyrenee: I’ll add a 30‑gram whey shake after the run and cut 200 kcal from lunch next week. I’ll log everything and watch HRV. Did you notice any HRV or liver changes when you cut calories? Also, have you tried a protein‑rich snack right after workouts to blunt the hunger spike?
  • dailyrenee: I haven’t cut back yet – still on 15 mg. I did a protein shake right after the run last week, 20 g whey, but the stomach still felt fuller than normal. HRV dipped slightly that day, maybe the shake timing helped a bit but not enough to stop the craving for a carb hit next meal. Did you notice a drop in post‑run energy when you lowered to 5 mg, and how big was the protein snack? That’ll help me decide when to tweak.

Community discussion - research and educational context only. Not medical advice.