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Glynac study from 2023 shows real mitochondrial boost – my take

Posted by hank_m in Research & News - 1 points, 4 comments.

gov/32999026/ – the folks saw a 20‑30 % increase in glutathione, better muscle strength and a drop in markers of inflammation, all after about six weeks of taking 100 mg/kg glycine and 100 mg/kg NAC daily (split into two doses). I’m not a scientist but the numbers look solid and i’ve tried the oral combo a bit – i felt less sluggish around meals and my sleep got a touch steadier, though i’m not sure if that’s real or placebo. The over‑hype tends to be that glynac will fix everything, but i think it’s a useful tool to keep the redox balance good, especially if you’re training hard or aging.

Has anyone here paired glynac with any specific training routine or diet? Would love to hear how others handle the dosing and if they notice anything beyond the obvious fatigue lift.

Comments

  • grace_sleepnerd: I ain’t used Glynac yet, but I’ve been on NAC 600 mg a day with a 1‑hour post‑workout protein shake for the last three months. I noticed a bit more endurance on the bench press, and FAMILY said I seemed less cranky after my meals. I keep my carbs trimmed, usually around 30‑40 g a day, and I do 5‑day split lifts – 3 days heavy, 2 days moderate. If I ever try the 100 mg/kg split, I’ll probably do it in the morning and late afternoon, and see if it keeps my soreness down. IMO, it’s probably more o
  • sarah_c: Fwiw I’ve tried a similar split – 500 mg glycine + 500 mg NAC twice daily – and noticed steadier energy during my afternoon lifts, though the soreness didn’t change much for me. Have you tracked any recovery metrics like DOMS or HRV?
  • hank_m: Tbh thanks sarah_c for the details, i’ve been doing 500 mg glycine+500 mg NAC twice a day too, so we’re on the same page, but i kept an eye on sleep and found it a tad steadier, same as you saw with energy – soreness stayed about the same, not a big win there. I haven’t been logging HRV or DOMS with the combo, so curious if that’s a metric you track and see any shift after a few weeks?
  • hank_m: I see you’ve been on 600 mg NAC with a post‑workout shake for three months and that bench press endurance went up, and that your family noticed a gentler mood after meals, nice parallels to what i felt on glynac. I keep my carbs tight around 30‑40 g and do a 5‑day split, heavy three days, moderate two, which is similar to your routine, so i’d love to hear if you notice any difference in recovery or energy when you add the 100 mg/kg glynac split at morning and late afternoon. What’s your take on

Community discussion - research and educational context only. Not medical advice.