ResearchSafe

Activated charcoal and my NR routine – any pointers?

Posted by greg208 in Safety & Side Effects - 2 points, 3 comments.

I’ve been using 500 mg of activated charcoal twice daily to tackle a bit of mold exposure at home. It’s been handy for clearing up the occasional gas and the black stools, but I’ve started noticing a drop in how bwe my nicotinamide riboside (NR) feels. I usually take 250 mg NR each morning – with breakfast and a cup of tea – but lately my energy levels are a tad assassination.

I’m not sure if the charcoal is binding the NR in the gut and cutting down its absorption. I’ve read that it can bind a lot of meds and nutrients, so I’m wondering if I should space the charcoal a full hour or two away from the NR, or maybe take NR on an empty stomach instead? Anyone else experience a similar hiccup, or any tricks to keep my NAD+ levels ticking while still using the charcoal? Cheers for the thoughtsμένο.

Comments

  • liam_sleepnerd: I’ve been doing the same combo for a few months. Activated charcoal will bind a lot of small molecules, so I usually put a 2‑hour gap between charcoal and any supplement that’s water‑soluble. For NR I shifted it to 30 min after my breakfast instead of first thing in the morning, and the energy spike came back. I didn’t move it to an empty stomach because I noticed stomach discomfort when I took it on an empty belly. Also, I keep a 24‑hour window check on my HRV and a quick lab for NAD+ every fe
  • greg208: Thanks for the tweak, liam. I'll shift NR to 30 min after breakfast as you did, and see if the spike comes back. I haven't done a formal NAD+ lab yet, but I could start a quick check in two months. Do you notice any changes in HRV when you move the timing? Also, any idea how long the charcoal stays in the gut?
  • grace_sleepnerd: Thanks, that makes sense. I’ve tried moving NR 30‑min after breakfast, but still give charcoal an hour later. My energy is back up, but I’ve noticed a slight stomach itch sometimes. Do you ever split the charcoal into two smaller doses? Also, how often do you check HRV?

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