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Question about Urolithin A dose and timing – any thoughts?

Posted by grace_sleepnerd in Longevity & Anti-Aging - 0 points, 4 comments.

I started taking Urolithin A about three weeks ago at 500 mg each morning with breakfast. I’m mainly interested in the mitophagy angle for muscle recovery after my weekend hikes. So far I haven’t noticed any GI upset but I also don’t feel a clear boost in endurance yet.

Maybe it’s too early or maybe the dose is low for me. I’ve read that some folks go up to 1000 mg split twice a day but I’m not sure if that’s necessary or if timing matters more with food versus empty stomach. Has anyone here tried a higher dose or taken it later in the day and felt a difference in energy or recovery?

Also curious if you cycle it or just keep it steady. Thanks for any input y’all have. Imo it’s worth sharing what works for you even if it’s just anecdotal.

Comments

  • greg208: Heard you’re into Urolithin A for mitophagy after hikes, solid angle. I’ve never tried it myself, but from what i’ve read (and a bit of trial with other compounds), timing could matter more than dose for some. I’ve seen people split doses to avoid GI stuff, but you’re fine with 500mg morn. Maybe try bumping to 750mg or so and see if that shifts anything? Or take it post-workout instead of breakfast?
  • aspiring_trailrun: Thanks greg208. I’ve stuck with 500mg morning with food, no GI issues. I’ll try 750mg split post‑hike and see if recovery feels sharper. Any idea how long to wait before judging?
  • grace_sleepnerd: I’ve been at 500mg morning for three weeks with no clear boost yet, maybe mitophagy’s slow. If you try 750mg post-hike, give it 4-6 weeks to see if recovery sharpens. Have you noticed any subtle changes, like less soreness or faster bounce back? Let me know how it goes!
  • grace_sleepnerd: Thanks for the 750mg and post-workout ideas. I’ll try 750mg after my hikes instead of breakfast this week, seen if that shifts recovery without messing up my sleep. If it helps, might ditch morning dosing entirely. Curious if you’ve tried post-workout timing before? (IMO, timing’s the bigger variable here.)

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