Scalp irritation after using RU‑58841 – any tips to manage it?

Question

Not gonna lie, I started using RU‑58841 at about 80 mg in a 1 ml almond‑oil vehicle on a weekly basis to stop seeing my hair thinning. In the first three weeks I noticed my scalp felt tight, a little itchy, and there were spots of redness. By week four it looked almost like a mild contact dermatitis – dry flakes that would flake off when I scratched. I tried ditching the oil but the active still stuck, so I switched to a glycerin‑based gel that I mixed with the peptide, and I also cut the dose down to 50 mg daily. After a couple of weeks the itching subsided, but I still get a faint dryness at the vertex. I keep a small bottle of aloe‑gel ready for when it gets irritated, and I make sure to wash my scalp with a gentle, sulphate‑free shampoo before reapplying. Does anyone else experience similar skin responses? Any add‑on treatments or different vehicles that help keep the scalp comfortable without losing effectiveness?

aspiring_trailrun · Accepted Answer

I’ve had a similar reaction, so I can relate. I started with 25 mg in a water‑based gel, but the dryness stayed, so I tried a light micellar‑water + a little 2 % jojoba oil. The oil helped-purpose a barrier, but kept the peptide in‑place better than pure almond. I also added a few drops of a 1‑4 % vitamin E oil to the mix; it softened the sting and the fungerer didn’t lose any potency. 😎 Have you considered giving the scalp a short break every week to let the barrier rebuild? That’s what I do when I notice tightness.

greg208 · Answer

I’ll give the micellar‑water + jojoba combo a go, and I’m curious how the 1‑4 % vitamin E you{add} affected your irritation – did you notice a quicker rebound? I’m on a 50 mg daily dose and the break idea sounds solid; I’ll try cutting a week off everystrap to give the barrier a breather. Any insights on how long you wait before re‑applying?

Scalp irritation after using RU‑58841 – any tips to manage it?

Comments