Timing BPC‑157 oral with TB‑500 twice‑weekly for chronic patellar tendon pain

Posted by trevor_recovery in Protocols & Stacks - 1 points, 0 comments.

I’ve been dealing with a nagging patellar tendon ache for about 8 months, and after trying NSAIDs and physio with limited results I started a self‑administered peptide routine. My current stack is 500 µg BPC‑157 taken orally each morning on an empty stomach, and 2.5 mg TB‑500 injected subcutaneously on Monday and Thursday evenings. I reconstitute BPC‑157 in 2 ml bacteriostatic water (250 µg/ml) and take 2 ml daily, while TB‑500 is mixed to 5 mg/ml and I draw 0.5 ml per injection.

So far, after 4 weeks I notice less morning stiffness and a small improvement in squat depth, but the tendon still feels tender after heavy leg days. I’m wondering if the timing could be optimized: should I take BPC‑157 closer to my workouts, or perhaps split the dose into pre‑ and post‑exercise? Also, would adding a low‑dose GHK‑Cu (200 µg daily) help with collagen remodeling around the tendon, or would that just increase injection frequency without clear benefit? Any thoughts on adjusting the TB‑500 frequency, maybe adding a third dose on Saturday, or using a slightly higher BPC‑157 dose (up to 750 µg) would be safe? I’m looking for feedback on the timing, dosing math, and whether adding a third component makes sense for my goal. Ngl, I’m open to trying a short 6‑week cycle and then reassessing. Thanks.

Community discussion - research and educational context only. Not medical advice.