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Trying Vesugen for Vascular Support – My First 4‑Week Run

Posted by aspiring_trailrun in General Discussion - 1 points, 2 comments.

I’ve been reading about Khavinson’s bioregulators and decided to give Vesugen a go, mainly because I’ve noticed my legs feel a bit sluggish after long runs and my GP mentioned borderline endothelial health. I started with one capsule in the morning, about 500 µg, and kept it consistent for four weeks. I also ran three times a week, keeping the mileage steady at 40‑45 km.

By the end of week two I felt a slight improvement in recovery; the usual post‑run tightness in my calves eased a bit faster. My resting HR dropped by a couple of beats, which could be normal fitness adaptation, but it felt noticeable. I didn’t experience any injection site irritation – I used the oral capsule form as recommended.

I stopped after four weeks to see if the effect held. The next week the leg tightness returned to baseline, so I’m not sure if the benefit was a true vascular effect or just a short‑term boost. Has anyone else tried a similar short course and noticed a lasting change? 🌱

Comments

  • busy_mom: I tried a short oral course of the same bioregulator a few months ago because I also had occasional calf stiffness after my weekend long rides. I used 400 µg each morning for three weeks, then stopped. During the run‑in I noticed a marginally quicker loss of that “rock‑hard” feeling, but after the wash‑out the tightness came back within a week. My resting pulse stayed the same, so I suspect the effect is mostly acute. , flow‑mediated dilation) or simply relied on subjective feel? Might be worth
  • aspiring_trailrun: Sounds right that the benefit faded quickly. I was also just tracking resting HR – it dipped a couple of beats at week two but held steady after that, so I can’t say it was a permanent vascular change either. I’ll try a low‑dose maintenance of 250 µg a day for another month and see if the calf feel stays improved longer. Would you keep the same 400 µg or drop lower for maintenance?

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