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Silicon Valley’s longevity hype might be a mirage

Posted by liam_sleepnerd in Research & News - 1 points, 5 comments.

https://www.techspot.com/news/112884-silicon-valley-longevity-drug-obsession-facing-first-real.html

This article talks about how Silicon Valley’s obsession with longevity drugs, like rapamycin and ketone supplements, is finally facing reality. The author argues that the evidence for these treatments isn’t as strong as social media or tech influencers suggest. Tbh, this aligns with my experience with Adamax.

I tried it for focus, but honestly, the results were all over the place. Maybe it’s placebo or individual variation. The article seems to get it right about the overhype, but it leaves out how these compounds could work in theory.

Comments

  • avery_c: I’ve dabbled with rapamycin myself in a very low‑dose, periodic protocol to keep my mTOR signaling in check, and I’m not surprised the human data feels patchy. The theory, that slowing mTOR slows cellular senescence and thus aging, has a solid mechanistic base, but the translation to everyday benefit is still murky. With Adamax, I’ve seen the focus spikes you mention, but only when paired with a consistent sleep routine and a light post‑breakfast carb load, so the day‑to‑day variability feels mo
  • sasha_climbs: I did log sleep with my Oura and took morning cortisol saliva strips for a month. Sleep scores stayed flat, cortisol didn’t shift, and focus felt no better on days I logged high sleep quality. Just my own data.
  • liam_sleepnerd: I did a 3‑month Oura log and 30‑day cortisol strips too, and the numbers stayed pretty flat – HRV hovered around 45‑55 ms, sleep scores stuck in the 80‑82 range, and morning cortisol never dropped below 10 µg/dL. Focus was a patchwork, sometimes a bit sharper after a good night but no clear pattern. Did you collect the saliva first thing in the morning or later? I found a difference if I took it right after waking vs. mid‑morning. That might explain why your scores stayed even. Also, what suppl
  • liam_sleepnerd: I’ve been logging HRV, total sleep time, and REM percentages on a nightly basis for the past three months, but I haven’t yet paired that with rapamycin or Adamax. Your point about the light post‑breakfast carb load aligning with focus spikes is interesting; I usually keep carbs around 30–45 g after breakfast, but I’m curious how you structure that load, timomite, carb type, or just a quick banana? Also, what biomarkers do you track on your rapamycin protocol to gauge mTOR activity?
  • nerdy_hikes: I took saliva right after waking, before coffee. My regime was just Adamax 10 mg daily, no other nootropics. Maybe timing matters? 🤓

Community discussion - research and educational context only. Not medical advice.