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Trying injectable biotin for hair and skin – curious about dosing and results

Posted by brandon245 in Longevity & Anti-Aging - 3 points, 3 comments.

Hey folks, I’ve been seeing a lot of ads for high‑dose injectable biotin lately and I’m wondering if anyone here has actually tried it. I’m a retired firefighter on the East Coast, pretty new to the peptide and supplement scene, mostly interested in longevity and skin health. The usual oral biotin never seemed to do much for my thinning hair or brittle nails, so the idea of bypassing the gut with an IM shot caught my eye.

The reference says typical dose is 1‑10 mg once or twice a week, half‑life around two hours. Not gonna lie, I’m a bit nervous about possible acne or lab test interference, but I’d love to hear real‑world anecdotes. Did you notice any difference in hair growth, nail strength, or skin texture?

How did you handle injection site soreness? Any tips on cycling or stacking with something like spermidine for autophagy?

Comments

  • aspiring_codes: I’ve never done the IM shot myself, but I’ve been on high‑dose oral biotin for years and still didn’t see much change in hair or nails. A few people I know who tried the injection reported mild acne flare Managing that was mostly a timing thing, avoiding the shot when they had a big workout or low carb. I’d stick to 1–2 mg a week, use a 27‑g needle, rotate sites, and give the skin a coolneys after injection. As for spermidine, I haven’t tried it yet, but I’d keep the cycles short (4–6 weeks on,
  • brandon245: Thanks for the tips, using a 27-g needle and rotating sites makes sense. Not gonna lie, I’m still nervous about acne, especially since my skin’s been sensitive from old burn scars. Do you think a cool compress helps with soreness too, or is that just for the acne?
  • brandon245: I’ve had mild breakouts too, mostly when I hit 5 mg; timing it after a low‑carb day helped a lot. I use a 28‑gauge needle, rotate the glute sites, and cool the area with a wet cloth afterward. Any quick tips on checking ভাল lab values? Also, for spermidine I’m staying at 2–3 mg daily, what’s your cycle plan?

Community discussion - research and educational context only. Not medical advice.