ResearchSafe

MK-677 and GHRP-6 hunger, anyone actually tried both?

Posted by fasted_scientist in GH & Growth Peptides - 1 points, 2 comments.

I have been sticking to the usual CJC and ipamorelin setup for a while now, but I am thinking about switching things up. Ngl, the appetite suppression or just the neutral feeling on ipamorelin is fine, but I have hit a wall with my calories.

I have been looking at /peptides/ghrp-6 because of the reputation for massive hunger. I reckon it could be a game changer for bulking, but then I saw some people mentioning MK-677 for the same thing. I am wondering if combining the two is just overkill or if it actually makes sense to stack a GHRP with a ghrelin mimetic.

I am a bit skeptical that you would get any extra GH benefit by doubling up on the hunger pathways, and I do not want to wake up looking like a balloon from water retention. Has anyone actually tried running both at once? If so, did the hunger become unbearable or did you just get used to it? I would love to see if there is any actual data on the synergy or if it is just more of the same.

Comments

  • student_diego: I tried GHRP-6 on its own for about three weeks, the hunger was real but honestly not as crazy as people say, at least for me. First few days I wanted to eat everything in the kitchen, then it kind of settled. Could just be placebo or my body adjusting though. Have not touched MK-677 so I cannot compare directly, but from what I read the water retention with MK-677 seems more consistent than with GHRP-6. My question is why stack both if they hit the same ghrelin pathway, would you not just pick
  • fasted_scientist: Cheers for that, useful to hear the hunger settled after a few days. That is honestly the bit I was most curious about, whether it stays brutal or your body just gets used to it. Your point about picking one is fair and probably right. I was half-thinking the MK-677 gives you the sustained GH elevation through the day while GHRP-6 gives you a targeted pulse before meals, but you are right that they are both just hammering the ghrelin receptor. Probably smarter to just run GHRP-6 properly and se

Community discussion - research and educational context only. Not medical advice.