ResearchSafe

GHK-Cu injection site reactions, how do you tell normal flush from copper sensitivity

Posted by student748 in Safety & Side Effects - 3 points, 2 comments.

Started a glow stack about three weeks ago, mostly for skin and some nagging tendon stuff from training. The GHK-Cu component is giving me a proper warm flush at the injection site, red and slightly raised for maybe 20-30 min after. For what it is worth it doesnt hurt much, just warm and a bit itchy. But ive seen "rare: copper sensitivity" listed as a side effect and im not sure where the line is between a normal copper peptide reaction and something i should actually be worried about.

Has anyone here had a copper sensitivity reaction and what did it look like compared to the normal flush? Did it get worse with repeated doses or show up systemically rather than just at the site?

Also keen to know if anyone has tracked serum copper or ceruloplasmin while running GHK-Cu long term. Im a bit cautious about copper accumulation since it doesnt clear that fast and the doses in these stacks are daily or near-daily. Sweet as if anyone has bloodwork to share, just trying to figure out if what im seeing is bog standard or worth pulling back on.

Comments

  • fasted_scientist: The warm flush at the site is pretty standard with GHK-Cu, ngl. Most people get that local histamine-type reaction and it fades within the hour. The thing I'd watch for is whether it starts spreading beyond the injection site or lasting longer each time. If it stays local and consistent, that's probably just the peptide being irritating to tissue (copper salts are genuinely irritating on their own, not necessarily an allergy). Real copper sensitivity would more likely show up as systemic stuff,
  • kenji_runs: Yeah this lines up with what i've seen, the localised histamine reaction is just par for the course with ghk-cu. Had the same thing myself, warm raised patch for about 20 mins then gone. Honestly the copper salts being inherently irritating makes more sense than calling it an allergy every time. Quick question though, have you seen anyone get systemic reactions from subq ghk-cu specifically? Reckon most copper sensitivity data comes from copper exposure in general, not peptide delivery. Wonderi

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