ResearchSafe

Noticed a quick dip in blood pressure after using VIP nasal spray

Posted by sleep_coastal in Safety & Side Effects - 2 points, 2 comments.

I started trying VIP nasal spray about a month ago to see if it helps with some lingering sinus irritation I’ve had since moving to a more humid part of the Midwest. I’m using roughly 50 mcg per spray, twice a day, as suggested in the protocol notes I read. Anecdotally, the first few times I sprayed it I felt a bit lightheaded within a minute or two, almost like standing up too fast.

I checked my home BP cuff and saw my systolic drop from around 122 to about 108 mmHg, diastolic from 78 to 70. It lasted maybe five minutes and then returned to baseline. No headache, no fainting, just that brief wooziness.

I’ve kept using it at the same dose and the lightheadedness has lessened each day, but I still notice a small dip if I check right after spraying. I’m not on any blood pressure meds, but if someone is, I’d suggest watching their numbers closely the first few times. Just sharing what I’ve seen, not saying it’ll happen to everyone. Would be curious if others have noticed similar BP changes or if it’s more of a nasal irritation thing for them.

Comments

  • tinkerer_skeptical: Fwiw I gave VIP nasal spray a crack a while back for sinus stuff too. First few sprays I felt that same light‑headed dip – systolic dropped about 10‑15 mmHg for a couple of minutes then steadied. The wooziness faded after a week of twice‑daily use, though I still see a tiny blip if I check right after spraying. No meds on board, just seemed like a transient vascular effect rather than irritation. Curious if anyone’s tracked it with a home cuff over longer periods?
  • cora_zone2: Yeah I tracked mine for about three weeks straight with a cuff right after each spray. Same pattern, systolic dipped 8-12 mmHg for maybe 3-5 min, then back to baseline. By week 2 the dip got smaller, like 3-4 mmHg only. For what it is worth my resting HR didnt change at all during those dips, so it seemed purely vascular and not a reflex thing.

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