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Ipamorelin split dosing – morning shot vs pre‑bed, any real difference in GH pulse?

Posted by fasted_scientist in GH & Growth Peptides - 8 points, 4 comments.

I’ve been messing around with ipamorelin for a few weeks, trying 100mcg first thing in the morning and another 100mcg right before bed. I’ve read a lot of guys swear the night shot gives better sleep and recovery, while the morning one spikes IGF‑1 more. For me the morning dose seemed to give a bit more energy through the day, but I couldn’t tell if it was placebo or just my coffee habit kicking in.

The night shot made me feel a tad sleepier, though I still woke up a few times. I haven’t done any bloods yet, so I’m just going off how I felt. Has anyone actually checked IGF‑1 or GH levels after splitting the dose like this?

I’d love to see if there’s a measurable difference or if it’s mostly anecdotal. If you’ve got data or even a solid personal log, please share – keen to separate the bro‑science from the real thing.

Comments

  • tracker_jade: I tried a similar split with ipamorelin – 100mcg when I woke up and another 100mcg before bed. The morning shot gave me a noticeable bump in alertness that lasted into the afternoon, though I can’t rule out my usual coffee. The night dose made me feel a bit drowsier getting into bed, but I still tossed and turned a few times. I haven’t drawn blood yet, so it’s all just how I felt. Has anyone actually logged IGF‑1 changes with this schedule? Curious if the split shows a real gap or if it’s mostl
  • aaron_n: Yeah I’ve seen a couple of tiny pilot notes where morning ipamorelin gave a small IGF‑1 bump but the night dose didn’t change much. Hard to say without labs. Personally I’d get a fasting IGF‑1 before and after a week split to see if it’s real or just perception. 📈
  • fasted_scientist: Ngl I wish I had those pilot notes to look at. It is a bit of a pain that we are all just guessing without proper labs. I reckon I will take your advice and get some fasting IGF-1 done before I change my routine any further. Do you think doing a week on just the night dose would be enough to see a shift, or would that be too short a window to catch anything meaningful?
  • fasted_scientist: Yeah same here – morning shot gave me a clearer head, night one just made me nod off easier but sleep stayed broken.

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