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BPC-157 oral vs injectable for a stubborn partial supraspinatus tear, what worked for you

Posted by tracker_jade in Healing & Recovery - 1 points, 6 comments.

Got an MRI showing a partial thickness supraspinatus tear that's been hanging around for months. Rotation with overhead press still flares it, sleep on that side is rough. I've been doing slow eccentrics and band work but progress is painfully incremental.

I've run injectable BPC-157 before for an Achilles issue and it seemed to help, anecdotally at least. This time I'm wondering if going oral makes more sense since I'd be on it for a while and don't love pinning daily for months. The arginate salt version is what people seem to talk about for systemic use.

For anyone who's dealt with a rotator cuff issue specifically, did oral feel like it did anything for tendon healing, or is injectable still the move for something this stubborn? Also curious if you stacked anything else or just kept it simple. Trying to figure out a realistic plan before I commit to another long run.

Comments

  • humble_labrat: Inj was achilles too so i feel you on the patience part. For something like a supraspinatus partial tear though, oral arginate salt is a pretty big question mark honestly. Most of the actual healing data on BPC is in animal models and injectable. The oral stability claims you see floating around forums... Id want to see the study before i just took someones word for it that it survives gut acid and actually makes it to the tendon. For a shoulder that stubborn id probably stick with injectable
  • luis_b: Yeah the oral stability thing has bugged me too. I split the difference when I did mine, did injectable close to the site for the first few weeks then moved to arginate salt oral for the longer tail. Felt like it helped but honestly could be placebo. The local injection part actually made my shoulder noticeably less angry within like a week, that part didnt feel like placebo at all.
  • grinder265: Yeah exactly, the local injection angle is what sold me on it last time too. Ngl oral sounds easier but if the bioavailability is BS then ur just buying expensive water. How close to the joint were u going with it, like anterior delt or actually around the supraspinatus insertion?
  • tracker_jade: I pinned subq in my belly last time for the Achilles, not local, so I can't speak to periarticular placement at all honestly. That's part of why I'm hesitant, the Achilles felt systemic-ish so oral might cover it, but a shoulder tear feels like it could use targeted delivery. How did you actually get it close to the insertion, ultrasound guided or just blind?
  • tracker_jade: Splitting it like that actually makes a lot of sense, local first then oral to keep things rolling. I'm a little sketched on shoulder injections because of where you'd have to go, so how did you handle the local piece, like who was doing it for you? Also did you pair anything with it during the oral tail or just ran it solo?
  • tracker_jade: Yeah that's fair, I've been leaning that way too honestly. Local pinning close to the supraspinatus makes more sense than hoping oral survives the gut. How close to the joint did you actually go with your Achilles, like right at the tendon or just in the general area? I keep reading different things on whether subQ near the site even matters versus just systemic.

Community discussion - research and educational context only. Not medical advice.