ResearchSafe

Two deaths in NI reported to the watchdog, over 500 adverse reaction reports total

Posted by erin_rows in Weight Loss & Metabolic - 3 points, 6 comments.

https://www.bbc.com/news/articles/ce3g5e79y4jo

BBC is reporting two deaths in Northern Ireland potentially linked to weight loss jabs, sitting inside a bigger pile of over 500 suspected adverse drug reactions sent to the regulator.

To be fair, "potentially linked" does a lot of heavy lifting in that sentence, and the MHRA yellow card system captures any report, not confirmed causality. Still, this is the conversation we keep avoiding. Most people I know on these started them without a proper medication review, no baseline bloods, no plan for what happens when they stop.

The bit that bothers me most is nobody talks about what the exit strategy looks like. You stop the jab, the appetite comes back with interest, and now you've lost lean mass you didn't track because nobody measured it.

Anyone here actually kept the weight off a year after stopping, or is everyone just planning to stay on it forever and hoping the long term data turns out grand?

Comments

  • tracker_jade: GLP-1s are a big topic here and I want to read more on them. Anecdotally, I see way more reports where folks gained it back within months of stopping. The lean mass part is what gets me too. Nobody is doing DEXA scans before or after, they just see the scale drop and feel good about it. Then they stop, appetite returns, and the weight comes back, but a chunk of what they lost was muscle. Question for anyone who's been on them a while. Did anyone actually get a proper medication review or basel
  • rachel_ketogen: Honestly the telehealth piece is where the safety net falls apart. My quick look at this, most of the people I know got a 10 minute call, no bloods ordered, no one asking what other meds theyre on. The prescriber just checks if you meet BMI criteria and ships it. I push for labs every time someone asks me. Full panel, A1C, lipids, the works. Its wild how often their own doctor never ran those to begin with. You cant track what you never measured 😅 DEXA is a good call though, im curious what p
  • humbleomar229: Bet it was a 5 minute telehealth form and a "have you got a credit card" check The muscle loss thing is proper grim though, seen people come off these jabs looking like melted candles. You'd think with all the hype someone would push for DEXA before/after but nah, scale goes down = win apparently Anyone here actually track lean mass while on one of these?
  • erin_rows: Fair play, the telehealth point is bang on. Half the people I know got their script from a two minute form, no bloods, no nothing. And yeah I'm tracking lean mass, had a DEXA before I started and booked another for month six. Scale only tells you so much. If you're losing weight but a chunk of it is muscle you're basically paying to get worse, not better.
  • erin_rows: The 10 minute call thing is gas. You'd spend longer on hold with the HSE than some people spend getting prescribed a GLP-1. I haven't done a DEXA yet myself, to be fair. Been meaning to book one but I keep spending the money on other things. Would love to know what people are actually losing in lean mass though, because if it's the usual "20 percent of weight lost is muscle" figure floating around, that's a rough trade.
  • erin_rows: Honestly no, I didn't get proper bloods before mine, just a telehealth form and a few questions about my weight history. I asked about DEXA and the prescriber looked at me like I had two heads. To be fair, I got mine privately so that might be why, but it's mad that "baseline bloods" is treated like a big ask when it's literally just blood. The lean mass thing is what I keep coming back to too. I lift, I track my protein, and I still felt weaker during the loss phase. Hard to say how much was
  • rachel_ketogen: Yeah the 10 minute consult is wild when you're getting a drug that tanks your appetite for months. I did get a DEXA before starting and again at month 4, lost about 22 lbs total and roughly 4 lbs of it was lean mass so around 18 percent for me. Protein intake made a real difference, i was hitting 130g+ daily. The 20 percent figure gets thrown around a lot but ive seen it vary pretty widely depending on what people eat and whether they lift.

Community discussion - research and educational context only. Not medical advice.