ResearchSafe

BPC-157 + TB-500 base with GHK-Cu added at week 3, anyone running a similar timing?

Posted by runner_aaron in Protocols & Stacks - 4 points, 4 comments.

Howzit, keen to get thoughts on a protocol I'm lining up for a niggling proximal biceps tendon that's been hanging around for months now.

Planning to run a Wolverine base first, so BPC-157 daily at 500mcg subq near the tendon, plus TB-500 at 2.5mg twice a week. From everything I've read and felt before, that combo on its own does solid work on tendon stuff, but I want to layer in GHK-Cu at around the 3 week mark, 200mcg a day, mostly for the collagen synthesis angle and because the area feels a bit stuck in its healing cycle tbh.

Main question is timing. Does adding GHK-Cu at week 3 actually make sense once the initial inflammatory phase has settled, or am I better off starting everything on day one? Also curious whether anyone splits the BPC-157 between local subq and a bit oral, or keeps it strictly one route for tendon work.

Cycle length is sitting around 8 to 10 weeks right now, with bloodwork before and after. Any input on the sequencing or the GHK-Cu add-on timing would be lekker.

Comments

  • tiredmira: Interesting stack you're putting together. For a tendon that's been stuck for months, waiting 3 weeks before adding GHK-Cu makes some sense to me since it does seem to work better once the initial healing is moving. I've done the opposite before and just layered everything from day one. Honestly couldn't tell if the timing mattered. 🤷‍♀️ Local subq vs oral for BPC is the question I've been going back and forth on too. For deep tendons like proximal biceps I'm not sure how much actually reache
  • runner_aaron: Fair enough. Yeah I think I'll stick with the week 3 add for GHK-Cu then, gives the inflammatory phase space to do its thing first. For BPC I'm gonna keep it strictly local subq near the tendon, oral just seems pointless for something this deep tbh. Range of motion tracking is a good call, I usually just eyeball pain but I'll actually measure it properly this time around.
  • greg208: Yeah timing makes sense to me as well, let the bpc and tb do the early lifting then bring ghk-cu in once things are moving. Not gonna lie i did the all-at-once thing once too and couldnt really tell what was doing what, which is partly why im thinking staggered this time. On the local vs systemic question, ive heard mixed things about how much actually migrates from subq near the site vs just general circulation. For a deep tendon like proximal biceps im probably leaning systemic just to cover
  • runner_aaron: Fair point on the all at once thing, that's partly why I'm staggering, harder to know what's pulling weight when everything lands day one. For ROM I'm just eyeballing it tbh, behind-the-back reach and a doorway stretch, nothing fancy. Pain-free flexion has crept up a few degrees since I started but I haven't been strict with numbers. Maybe I should actually start logging it properly so I can compare the pre and post GHK weeks, otherwise I'm just guessing. Did you find the systemic route actual

Community discussion - research and educational context only. Not medical advice.