My first 8‑week titration with Survodutide – appetite drop and a strange energy dip

Posted by wes_cycles in Weight Loss & Metabolic - 13 points, 4 comments.

I started Survodutide about two months ago after reading up on the dual GLP‑1/glucagon profile and thought the weekly injection would fit my schedule better than daily semaglutide. I began at 0.6 mg on week 1, felt a mild nausea on day 2 that settled after a night of extra water, and noticed my appetite was already down by roughly 30 % – I could skip my usual 300 kcal snack without feeling jittery.

From week 3 I upped to 1.2 mg and tracked my HRV; it dipped a bit for the first three nights (maybe the glucagon‑induced hepatic fat oxidation), but by day 5 it was back to baseline and my resting energy expenditure on the wearable seemed a touch higher. Weight loss was 1.8 kg over the first four weeks, mostly water and a little fat.

At week 6 I hit 2 mg and started feeling a low‑grade fatigue in the afternoons that wasn’t there before – I logged it as “energy dip” and added a short walk after lunch, which seemed to help. No diarrhea or constipation yet, just occasional mild constipation that cleared with a bit more fiber.

I’m curious if anyone else has felt that mid‑day slump when the dose passes the 2 mg mark, and how you manage it – more carbs, extra electrolytes, or just ride it out?

Comments

• gina_mobility: anecdotally i hit the 2 mg mark on survodutide a few weeks back and the same mid‑day slump showed up. it was kinda like a post‑lunch crash but without the food. i tried a 15‑minute walk and a splash of electrolytes (magnesium + potassium) and it shaved the dip in half. i also nudged my protein intake up a bit at lunch – chicken salad instead of a sandwich – and my HRV steadied after a couple of days. nothing dramatic, just tweaking the timing and a bit more carbs seemed to smooth it out. anyone
• wes_cycles: Interesting that you saw the same mid‑day slump. I actually tried the 15‑minute walk too but didn’t add electrolytes – after a week I still felt the dip, so I started sipping a magnesium‑glycinate 200 mg with a pinch of potassium chloride around 1300h. The fatigue dropped from a 3/10 to about 1‑2/10 and my HRV variance narrowed after two days. I also switched my lunch carbs from white rice to a 30 g quinoa bowl with mixed veg, keeping protein constant at ~35 g. That seemed to level the energy c
• aspiring_codes: That lines up with what I saw when I hit 1.5 mg – the slump felt like low‑blood‑sugar vibes even without eating. I also upped my lunch carbs (a sweet potato side) and added a quick walk. The dip eased pretty quickly, so tweaking macros and a bit of movement definitely helped. 👀
• wes_cycles: That sweet potato idea is steady, and it makes sense because i think i might be under eating too much. My energy dip at 2 mg felt exactly like that slump you mentioned, but i didnt really adjust my macros, i just tried the walking. I wonder if the glucagon part is making my blood sugar drop faster than the GLP-1 side is managing. I might try adding some slow carbs to lunch and see if my HRV stays more stable during the day.

Community discussion - research and educational context only. Not medical advice.