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TB-500 and BPC‑157 combo for hamstring tendon tear – timing question

Posted by casey613 in Healing & Recovery - 4 points, 4 comments.

I tore my right hamstring during a long rugby match last winter and spent a month in physiotherapy before my knee started feeling a bit stiff. After seeing a few case reports on TB‑500 and BPC‑157 in one of the forums, I decided to try a low‑dose protocol: TB‑500 2 mg twice a week and BPC‑157 2 mg once a week. I reconstitute both with bacteriostatic water, using a drop of acetic acid water if the powder is stubborn.

The first week I injected TB‑500 early in the morning and BPC‑157 around 18:00, hoping the staggered timing would keep the local inflammation controlled while the angiogenesis kicks in. I also added a topical hyaluronic‑acid serum twice a day because the joint still feels a bit clicky. After two weeks I noticed less swelling and a slight increase in flexibility, but I’m not sure if the 12‑hour gap between injections is optimal or if I could combine them on the same day without compromising the healing response. Does anyone have experience with same‑day injections or a different schedule that worked better?

Comments

  • sleep_coastal: I’ve played around with a similar stack for a nagging calf strain and found that hitting both peptides on the same day worked fine for me. I did TB‑500 first thing in the morning and BPC‑157 about eight hours later, then repeated the pattern every other day. Anecdotally the swelling dropped a bit faster than when I spaced them 12 hours apart, and I didn’t notice any extra irritation at the injection sites. Everyone’s response varies though, so if you try same‑day dosing keep an eye on how the a
  • steph414: I’ve tried a similar split but kept them 12 hours apart and didn’t see a clear difference in swelling. Did you notice any change in range of motion or just the swelling? Curious if the 8‑hour gap really speeds things up or if it’s just variability.
  • casey613: I didn’t actually measure ROM in a formal way – just felt the hamstring a bit less tight after the second week, and the swelling was noticeably less around the same time. I haven’t tried the same‑day 8‑hour gap yet, so I can’t compare, but I hadn’t seen a clear jump in motion either. Did you track swelling or pain levels daily, or was it just a general sense of improvement?
  • casey613: Your faster swelling reduction is tempting, but I’d still worry about compounding inflammation from TB-500’s longer action. Did you adjust doses when stacking? I’m curious if your calf strain was fresh vs. Lingering like mine was.

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