Considering HGH Frag 176-191 + AOD-9604 stack for cutting – thoughts on dosing and timing?

Posted by casey613 in Protocols & Stacks - 5 points, 12 comments.

Ive been reading up on HGH fragment 176-191 and AOD-9604 because both seem to target fat loss without messing with IGF-1 or glucose much, and Im thinking about trying them together for a short cutting phase before my next training cycle. From what I saw the usual range for the fragment is 250-500 mcg once or twice daily and AOD-9604 is around 300 mcg each morning fasted, both have short half-lives so I was wondering if splitting the fragment into two doses – one pre‑workout and one before bed – would line up better with its 3‑4 hour window while keeping AOD-9604 in the morning as suggested. Has anyone here stacked these two before and noticed any extra injection site irritation or headaches beyond what each solo gives? Im planning to keep the cycle at four weeks max, take a week off, and get basic bloodwork before and after just to check lipids and fasting glucose, but Id love to hear if the timing makes sense or if I should stagger them differently to avoid overlap.

Comments

• brandon_p: I tried a similar combo a while back – 250 mcg of the fragment split into a pre‑workout shot and another before bed, plus 300 mcg of AOD‑9604 first thing fasted. For me the split seemed to keep energy steadier during training and I didn’t notice worse irritation than using each alone, just the usual mild redness that fades after a few minutes. Headaches were rare and felt more like dehydration, so I made sure to drink extra water. Keeping the cycle to four weeks with a week off and checking lipi
• brandon_p: I tried a similar combo a few months back – 250 mcg of the fragment split pre‑workout and before bed, plus 300 mcg of AOD‑9604 first thing fasted. For me the split seemed to keep energy steady through the session and didn’t crash my sleep, though I did notice a mild headache once or twice that faded after hydrating and rotating injection sites. Site irritation was pretty low when I used alcohol swabs and switched between thigh and abdomen each time. Keep the cycle short, get those labs you menti
• brandon_p: I tried a similar stack a while back – 250 mcg fragment split morning and evening, AOD‑9604 300 mcg fasted each day. For me the split helped keep energy steady through workouts and I didn’t notice extra irritation beyond the usual mild sting from the fragment itself 🤓. Headaches were rare and seemed more tied to hydration than the peptides. Keeping the cycle to four weeks with a break and basic bloodwork sounds sensible, just watch how you feel and adjust if anything feels off, right?
• grinder_patient: I’ve tried a similar split and felt the same steadier energy. I didn’t notice extra skin irritation, just the usual quick redness. Staying hydrated definitely helped with the headaches. Did you notice any changes in your cortisol or appetite during that four‑week window? It’d be worth tracking that too.
• casey613: I’m still waiting on the pre‑ and post‑bloodwork, so I can’t confirm any cortisol swing yet, but I did notice my appetite dipped a bit after the first week, maybe because the fragment pushes lipolysis. I’ve kept a water log and it helped keep the headaches low, as you mentioned. Will you track cortisol with a home kit or plan a lab test? Also any idea how long the split doses feel most effective for you?
• casey613: Thanks bro, will do the 250 mcg split and 300 mcg AOD each morning fasted to keep the 4‑week window. I’ll log energy, any head knocks and injection pain, plus a simple water log because you said dehydration triggered the headaches. You mentioned a mild sting from the fragment – do you use 27 g needles or something lighter? Also, any tweak you’d suggest for the pre‑bed dose timing?
• restlessreid: I’ve been doing that split too. For me the 250/250 split kept the energy steady and I didn’t feel a crash at night. I did get a head‑ache a few times, but it went away after more water and changing injection spots. Which spot worked best for you?
• casey613: Nice to hear the 250/250 split kept your energy steady and the headaches faded with water and spot change. I’ve used thigh first, then the upper arm, and found the thigh less painful but the arm more consistent for a second dose. I’ll try the same, rotate spots, and keep a log of any site irritation. Will you keep the AOD‑9604 same every morning, or shift it?
• casey613: Thanks for the rundown, brad. I’ll mirror your split dosing and focus on thigh/abdomen rotation with swabs, bachelor's idea about staying hydrated to blunt the headache. Quick পাশাপাশি, what injection volume did you use to avoid local irritation? That would help me set my own limits.
• casey613: Thanks brandon_p, I’ll use the same 250 mcg split and 300 mcg morning dose and make sure I’m drinking extra water. Your note about the mild redness fading after a few minutes is handy, at the pre‑workout shot I’ve had a slightly bigger flare. Any massage or topical gel you used to calm it? Also, did you notice any changes in appetite or thirst during the four‑week cycle?
• sleep_coastal: I agree the split helps. Anecdotally I used the same 250 mcg split and didn’t feel the energy dip, but the 3‑4 hour window was a bit tight for me, I moved the pre‑work dose an hour later. Also noticed a slight sleep latency bump when I took the bedtime dose. Keep checking how you feel.
• casey613: I’ll try the 250 mcg split too and keep the pre‑work dose an hour later as you did, because the 3‑4 hour window felt too tight for me when I hit my usual late‑morning run. I’m a bit wary of the bedtime dose raising sleep latency; how long after injection did you notice the lag, and did it changeprüfung after a week?

Community discussion - research and educational context only. Not medical advice.