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AL-LAD vs Psilocybin

A side-by-side research comparison of AL-LAD and Psilocybin across mechanism, dosing, half-life, benefits, side effects and research status.

Comparison table

AttributeAL-LADPsilocybin
Full name6-Allyl-6-nor-LSDPsilocybin (from psilocybin mushrooms)
CategoryPsychedelicsPsychedelics
StatusSchedule I (research compound)Schedule I (FDA Breakthrough Therapy for depression)
MechanismActivates serotonin 5-HT2A receptors, like LSD.Converted in the body to psilocin, which activates serotonin 5-HT2A receptors in the brain. This temporarily loosens rigid thinking patterns and increases connectivity between brain networks.
Molecular weight349.47 g/mol284.25 g/mol
Half-life~3-4 hours~2-3 hours (psilocin)
BioavailabilityOralOral
Typical doseVaries by individual and setting10-30 mg in clinical trials
FrequencyOccasionalOne to a few supervised sessions
RouteOralOral, in a supervised therapeutic setting

AL-LAD reported benefits

  • Shorter than LSD
  • Reportedly less anxious
  • Strong visual component
  • Lysergamide research compound

Psilocybin reported benefits

  • Studied for treatment-resistant depression
  • Eases anxiety in life-threatening illness
  • Explored for alcohol and tobacco addiction
  • Often produces durable improvements after few doses

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Research and educational reference only. Not medical advice.